|July 15, 1998|
|April 23, 2003|
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- In the manga, Dominique commits suicide after losing the fight to Vash.
- The town where Vash uses his Angel Arm for the first time was the same one where he fought Dominique in the manga, where as in the anime Vash travels to another town before being forced to use it.
- All the Gung-Ho-Guns arrive in town for Knives' resurrection while Dominique fights Vash long enough so it can happen in the manga, in the anime they all do gather in town but leave and let Dominique handle Vash on her own as Knives was still recuperating during this point in the series.
- Vash battles one armed against the Cyclops since he had lost his left arm during the fight with Monev the Gale.
- Nicholas D. Wolfwood is revealed to be one of the Gung-Ho-Guns and is code named: Chapel and is in attendence for Knives' resurrection and Vash's Angel Arm going off but isn't noticed by Vash keeping his cover intact, unlike the anime in which he is only hired by them and is absent from the Angel Arm going off in Augusta only seeing the aftermath.
- In the Manga Vash sense his brothers return and uses that as his reasoning for abandoning Milly and Meryl in after his fight with Dominique. In the anime Vash abandons the two after realizing the danger they are both in with Gung-Ho-Guns hunting him.
- Milly and Meryl dont get to meet Dominique in the manga since she committed suicide after losing to Vash, where as in the anime they do get to meet her and misinterpret Vash's actions as being perverted with Dominique running off soon after.